Glutathione is a protein in the body that mainly works in the liver. It has been used as an antioxidant to slow damage to cells. Glutathione can be taken as a pill or powder. It can also be inhaled through the nose as a nasal spray. It can also be injected into muscle and the bloodstream by a healthcare provider.
There are no advised doses for glutathione.
Editorial process and description of evidence categories can be found at EBSCO NAT Editorial Process.
It is likely safe to take glutathione in small doses for a short time. Not enough studies have been done to say whether it is safe to use for a long period. It is also not known whether it is safe to take by women who are pregnant or breastfeeding.
Talk to your doctor about any supplements or therapy you would like to use. Some can interfere with treatment or make conditions worse.
A. Athletic Performance
A1. Hwang P, Morales Marroguín FE, et al. Eight weeks of resistance training in conjugation with glutathione and L-Citrulline supplementation increases lean mass and has no adverse effects on blood clinical safety markers in resistance-trained males. J Int Soc Sports Nutr. 2018;15(1):30.
B. Cystic Fibrosis
B1. Ciofu O, Lykkesfeldt J. Antioxidant supplementation for lung disease in cystic fibrosis. Cochrane Database Syst Rev. 2014;(8):CD007020.
Last reviewed February 2020 by EBSCO NAT Review Board Eric Hurwitz, DC Last Updated: 5/27/2020